La Salle University's Bachelor of Science in Nursing program prepares its graduates to qualify for the state board nursing examination (NCLEX-RN) to become registered professional nurses and to practice as members of the nursing profession. The four-year, full-time, 122-credit program leading to the BSN provides the student with a strong foundation in the liberal arts and biological sciences in preparation for 12 nursing major courses, eight of which include clinical practice components in a variety of health care settings. The goal of the B.S.N. program is to enable the graduate to provide professional nursing care which includes health promotion and maintenance, illness care, restoration, rehabilitation, and health counseling and education based on knowledge derived from nursing theory and research.

La Salle's B.S.N. program provides the opportunity to refine critical thinking skills, to strengthen one's self concept as a person, to develop as a member of the nursing profession, to set a course for self-directed learning and independent action, and to prepare for graduate study in nursing. The program is designed for students entering from high school who have selected nursing as a career, transfer students, adult students who are seeking a second undergraduate degree or career change, and students who have completed liberal arts/science pre-nursing requirements.