Thomas H. McPhillips, F.S.C., Ph.D.
Biology Department
La Salle University
Philadelphia, Pennsylvania
EDUCATION
La Salle College, Philadelphia, Pennsylvania, B.A., Biology
Villanova University, Villanova, Pennsylvania, M.S., Biology
Baylor College of Medicine, Houston, Texas, Ph.D., Virology and Epidemiology
TEACHING EXPERIENCE
Biology Department, Education Department, IAMST,: La Salle University, Philadelphia, Pennsylvania
Science Department: Bethlehem University, Bethlehem, West Bank Occupied Territories
Biology Department: Villanova University, Villanova, Pennsylvania
Science and Music Departments: South Hills Catholic High School, Pittsburgh, Pennsylvania
Science, Music, and Religion Departments: La Salle College High School, Philadelphia, Pennsylvania
Science faculty and Counseling staff: The Bridge Residential Drug Rehabilitation Center, Philadelphia, Pennsylvania
RESEARCH INTERESTS:
In the course of my career I have investigated the molecular biology and genetics of reoviruses and paramyxoviruses. Most recently I have been working with Dr. Siba K. Samal and his colleagues at the University of Maryland on the molecular and genetic characterization of a new genus of viruses, the Aquareoviruses.
SELECTED PUBLICATIONS
McPhillips, T.H., Dinan, D., Subramanian, K. and Samal, S.K. Enhancement of Aquareovirus infectivity by treatment with proteases: mechanism of action. Journal of Virology 72(4): 3387-3389, April, 1998.
Samal, S.K., McPhillips, T.H., Dinan, D. and Rockemann, D.D. Lack of restriction of growth for aquareovirus in mammalian cells. Archives of Virology 143(3): 571-579, 1998.
Subramanian, K., McPhillips, T.H. and Samal, S.K. Characterization of the polypeptides and determination of the genome coding assignments of an aquareovirus. Virology 205: 75-81, 1994
Samal, S.K., Pastey, M.J., McPhillips, T.H., Carmel, D.K. and Mohanty, S.B. Reliable confirmation of antibodies to Bovine Respiratory Syncytial Virus (BRSV) with an enzyme-linked immunosorbent assay using BRSV nucleocapsid protein expressed in insect cells. Journal of Clinical Microbiology, 31(12): 3147-3152, 1993.
Samal, S.K., Pastey, M.J., McPhillips, T.H. and Mohanty, S.B. Bovine respiratory syncytial virus nucleocapsid protein expressed in insect cells specifically interacts with the phosphoprotein and the M2 protein. Virology 193:470-473, 1993.
Samal, S.K., Zamora, M., McPhillips, T.H. and Mohanty, S.B. Molecular cloning and sequence analysis of bovine respiratory syncytial virus mRNA encoding the major nucleocapsid protein. Virology 179:453-456, 1991.
Marshall, S.H., Samal, S.K., McPhillips, T.H., Moore, A.R., and F.M. Hetrick. Isolation of a rotavirus from smelt, Osmerus mordax (Mitchell). Journal of Fish Diseases, 13:87-91, 1990.
Samal, S.K., Dopazo, C.P., McPhillips, T.H., Baya, A., Mohanty, S.B. and Hetrick, F.M. Molecular characterization of a rotaviruslike virus isolated from striped bass (Morone saxatilis). Journal of Virology 64(11):5235-5240, 1990.
Hetrick, F.M., Samal, S., Marshall, and McPhillips, T. Reoviruses of aquatic animals. In Recent Advances in Microbial Ecology: Proceedings of the Fifth International Symposium on Microbial Ecology, Kyoto, Japan, pp. 582-586, 1989.
Weiner, D. B., Gaulton, G., Girard, K., Williams, W., McPhillips, T. H., and Rubin, D. H. Reovirus type 1 and type 3 differ in their binding to isolated intestinal epithelial cells. Microbial Pathogenesis 5(1):29-40, 1988.
McPhillips, T. H. and Ramig, R. F. Extragenic suppression of temperature-sensitive phenotype in reovirus: Mapping suppressor mutations. Virology 135:428-439, 1984.